Mucositis Symptoms - Arbabi-kalati F, Arbabi-kalati F, Deghatipour M, Ansari Moghadam A Evaluation of the efficacy of zinc sulfate in the prevention of chemotherapy-induced mucositis: a double-blind randomized clinical trial Arch Iran Med. (2012 Jul)

Upper Respiratory Tract Infection Symptoms - Weismann K, Jakobsen JP, Weismann JE, Hammer UM, Nyholm SM, Hansen B, Lomholt KE, Schmidt K Zinc gluconate lozenges for common cold. A double-blind clinical trial Dan Med Bull. (1990 Jun)

Appointments at Mayo Clinic

Acne Symptoms - Brittany E Yee, Phillip Richards, Jennifer Y Sui, Amanda Fleming Marsch Serum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta-analysis Dermatol Ther. (2020 Aug 29) C D Hunt, P E Johnson, J Herbel, L K Mullen Effects of dietary zinc depletion on seminal volume and zinc loss, serum testosterone concentrations, and sperm morphology in young men Am J Clin Nutr. (1992 Jul)

Acne Symptoms - Göransson K, Lidén S, Odsell L Oral zinc in acne vulgaris: a clinical and methodological study Acta Derm Venereol. (1978) Wart Severity - Al-Gurairi FT, Al-Waiz M, Sharquie KE Oral zinc sulphate in the treatment of recalcitrant viral warts: randomized placebo-controlled clinical trial Br J Dermatol. (2002 Mar) As copper deficiency may also cause myeloneuropathy, physicians should be alert to sensory and motor symptoms and signs which may potentially indicate incipient neuropathy or myelopathy in patients treated with Wilzin. Camacho EM, Huhtaniemi IT, O'Neill TW, Finn JD, Pye SR, Lee DM, Tajar A, Bartfai G, Boonen S, Casanueva FF, Forti G, Giwercman A, Han TS, Kula K, Keevil B, Lean ME, Pendleton N, Punab M, Vanderschueren D, Wu FC, EMAS Group Age-associated changes in hypothalamic-pituitary-testicular function in middle-aged and older men are modified by weight change and lifestyle factors: longitudinal results from the European Male Ageing Study Eur J Endocrinol. (2013 Feb 20)Numerous products are advertised as testosterone boosters, but the vast majority don’t work, though some can make you believe they do by boosting your libido. Maca, for instance, can enhance libido without affecting testosterone. [114] [115] [116] [117] It also contains a solid dose (600 milligrams) of vitamin B12, which is beneficial for vegetarians, vegans, and older adults, along with those with digestive conditions. This supplement also contains 140 milligrams of lutein, which, along with zinc, may benefit people with or at risk of age-related macular degeneration, and it may play a role in reducing the risk of chronic diseases. Melville GW, Siegler JC, Marshall PW Three and six grams supplementation of d-aspartic acid in resistance trained men J Int Soc Sports Nutr. (2015 Apr 1) Costello RB, Moser-Veillon PB A review of magnesium intake in the elderly. A cause for concern? Magnes Res. (1992 Mar)

Nature’s Way Zinc is ConsumerLab.com approved, vegan, and contains no yeast, wheat, soy, dairy, or preservatives. Of note, it also contains vitamin C and echinacea, which can be helpful for immune support as well. You will also find stevia leaf and some sugar alcohols (sorbitol and mannitol) for sweetness. Sugar alcohols may cause some stomach bloating, and it’s also been shown that zinc supplements that contain these ingredients may have different levels of effectiveness for people as opposed to zinc on its own. Zinc gluconate is approximately 14% zinc by weight; therefore, 348 mg of zinc gluconate contains 50 mg of elemental zinc. In the blood, about 80% of absorbed zinc is distributed to erythrocytes, with most of the remainder being bound to albumin and other plasma proteins. The liver is the main storage for zinc and hepatic zinc levels are increased during maintenance therapy with zinc. General Oxidation - Seet RC, Lee CY, Lim EC, Quek AM, Huang H, Huang SH, Looi WF, Long LH, Halliwell B Oral zinc supplementation does not improve oxidative stress or vascular function in patients with type 2 diabetes with normal zinc levels Atherosclerosis. (2011 Nov) Dreno B, Amblard P, Agache P, Sirot S, Litoux P. Low doses of zinc gluconate for inflammatory acne. Acta Derm Venereol. 1989;69(6):541-543.

Zinc Supplement Safety and Side Effects

Merrells KJ, Blewett H, Jamieson JA, Taylor CG, Suh M Relationship between abnormal sperm morphology induced by dietary zinc deficiency and lipid composition in testes of growing rats. Br J Nutr. (2009-Jul) Ebben M, Lequerica A, Spielman A Effects of pyridoxine on dreaming: a preliminary study Percept Mot Skills. (2002 Feb) Overtraining, however, is counterproductive. Prolonged endurance exercise especially can cause your testosterone to drop. [87] [88] Ensuring adequate recovery time will help you receive the full benefits of physical activity. 3. Weight management Iron Absorption - J K Friel, R E Serfass, P V Fennessey, L V Miller, W L Andrews, B S Simmons, G F Downton, P G Kwa Elevated intakes of zinc in infant formulas don not interfere with iron absorption in premature infants J Pediatr Gastroenterol Nutr. (1998 Sep) Testosterone is an androgen, a male sex hormone, though women need it too. In men, low testosterone has been associated with low libido [72] and poor health outcomes, such as the development of metabolic syndrome. [73] In men and women, low testosterone has been associated with depression. [74] [75]

Rosacea Symptoms - Sharquie KE, Najim RA, Al-Salman HN Oral zinc sulfate in the treatment of rosacea: a double-blind, placebo-controlled study Int J Dermatol. (2006 Jul) gluconate, along with zinc acetate, The absorption of zinc may be reduced by iron and calcium supplements, tetracyclines and phosphorus-containing compounds, while zinc may reduce the absorption of iron, tetracyclines, fluoroquinolones. K Ryan Wessells, Kenneth H Brown Estimating the global prevalence of zinc deficiency: results based on zinc availability in national food supplies and the prevalence of stunting PLoS One. (2012) Psoriasis Symptoms - Sadeghian G, Ziaei H, Nilforoushzadeh MA Treatment of localized psoriasis with a topical formulation of zinc pyrithione Acta Dermatovenerol Alp Panonica Adriat. (2011)

4. Zinc Picolinate

van Ballegooijen AJ, Pilz S, Tomaschitz A, Grübler MR, Verheyen N. The synergistic interplay between vitamins D and K for bone and cardiovascular health: A narrative review. Int J Endocrinol. 2017;2017:7454376. doi:10.1155/2017/7454376 Topo E, Soricelli A, D'Aniello A, Ronsini S, D'Aniello G The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats Reprod Biol Endocrinol. (2009 Oct 27) Hemilä, H., Chalker, E. The effectiveness of high dose zinc acetate lozenges on various common cold symptoms: a meta-analysis. BMC Fam Pract 16, 24 (2015). https://doi.org/10.1186/s12875-015-0237-6 Lassi ZS, Moin A, Bhutta ZA Zinc supplementation for the prevention of pneumonia in children aged 2 months to 59 months. Cochrane Database Syst Rev. (2016-Dec-04)