Lin HH, Chen JH, Kuo WH, Wang CJ. Chemopreventive properties of Hibiscus sabdariffa L. on human gastric carcinoma cells through apoptosis induction and JNK/p38 MAPK signaling activation. Chem Biol Interact. 2007;165(1):59–75.

Hibiscus contains acids that act as chemical exfoliators and help to clear the clogged skin pores. It also has antibacterial properties that work to fight acne-causing bacteria on the skin. Thus, it prevents the formation of pimples. Your liver has several functions — such as producing proteins, secreting bile, and breaking down fat — that are essential to your overall health ( 14).

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Also, avoid metal utensils – they can create hot spots and burn the ingredients. Instead, use wooden or silicone utensils.

Nourish and nurture your scalp! Using Hibiscus Oil for Scalp Therapy will provide your follicles with vitamins and minerals. Massage it in for improved blood flow, to combat dandruff, and reduce itchiness and dryness. Herranz-López M, Olivares-Vicente M, Encinar JA, et al. Multi-targeted molecular effects of Hibiscus sabdariffa polyphenols: an opportunity for a global approach to obesity. Nutrients. 2017;9(8):907. Published 2017 Aug 20. https://doi.org/10.3390/nu9080907. Antidiabetic and anticancer effects are among the purported benefits of hibiscus. Hibiscus preparations may also help lower blood pressure, protect the liver, and decrease fasting blood sugar. Blood pressureA study in hamsters also demonstrated the potential liver-protecting properties of hibiscus extract, showing that treatment with hibiscus extract decreased markers of liver damage ( 16). Chiu CT, Chen JH, Chou FP, Lin HH. Hibiscus sabdariffa leaf extract inhibits human prostate Cancer cell invasion via Down-regulation of Akt/NF-kB/MMP-9 pathway. Nutrients. 2015;7(7):5065–87. Published 2015 Jun 24. https://doi.org/10.3390/nu7075065. It’s vital to rehydrate dried hibiscus flowers for the best flavor and texture in cooking. Here’s the simple way to do it:

Not just a pretty sight for a plant lover, but the beautiful and bright hibiscus flowers are also a great go-to for your hair woes. One of the most impressive and well-known benefits of hibiscus tea is that it may help lower blood pressure. Having grown up with hibiscus flowers, usually bight red with the long pistil reaching for the sun with yellow covered stamens prominently displayed and so familiar, I was captivated when I first found hibiscus seed oil from one of my suppliers. Oxidative stress is thought to contribute to chronic conditions such as high blood pressure, cancers, diabetes, and heart disease ( 3, 6, 7, 8). Annexin V binding assay and propidium iodide staining were performed to respectively monitor early apoptosis and cell permeabilization, a marker of necrotic or late apoptotic cell death. Cells were treated with various concentrations of hibiscus flower extract similar to those published previously with aqueous extracts of dandelion root and white tea [ 18, 19]. Cells were then treated individually or in combination with chemotherapeutics taxol, cisplatin, and tamoxifen as indicated in the results section. This protocol is similar to that previously published [ 18, 19]. Cells were washed with phosphate-buffered saline (PBS) and suspended in Annexin V binding buffer (10 mM HEPES, 140 mM NaCl, 2.5 mM CaCl 2, pH 7.4) with green fluorescent Annexin V AlexaFluor-488 (1:20) (Life Technologies Inc., Burlington, ON, CA, Cat No. A13201) and 0.01 mg/mL of red fluorescent PI (Life Technologies Inc., Burlington, ON, CA, Cat No. P3566) for 15 min at 37 °C protected from light. Percentage of early (green), late apoptotic cells (green and red), and necrotic cells (red) were quantified with a Tali Image-Based Cytometer (Life Technologies Inc., Burlington, ON, CA, Cat No. T10796). Cells from at least 18 random fields were analyzed using both the green (ex. 458 nm; em. 525/20 nm) and red (ex. 530 nm; em. 585 nm) channels. Fluorescent micrographs were taken at 400x magnification using LAS AF6000 software with a Leica DMI6000 fluorescent microscope (Wetzlar, Germany). Cells monitored with microscopy were counterstained with Hoechst 33342 (Molecular Probes, Eugene, OR, USA) with a final concentration of 10 μM during the 15-min incubation. Reactive oxygen species (ROS) quantification

Could this unusual fatty acid be the source of the gently and slightly exfoliating properties of the oil? Just by applying it as a light facial oil, it increases cell turnover. The results are subtle, but I find them noticeable over time. We have investigated aqueous hibiscus flower extract anticancer efficacy, selectivity, and interactions with chemotherapeutics taxol, cisplatin, and tamoxifen in estrogen-receptor positive breast cancer cells, triple-negative human breast cancer cells, and normal non-cancerous cells. Apoptotic morphology and biochemical marker expression were assessed to determine the extent anticancer efficacy of hibiscus. Mitochondrial membrane potential reduction and reactive oxygen species generation were quantified using fluorogenic dyes to determine the mechanism of hibiscus extract action. Results Morphological assays were conducted to assess the effect of treatments on cell morphology. Fluorescent microscopy using AV and PI after hibiscus treatments at 48 h confirmed apoptosis induction due to hibiscus. These apoptosis markers were observed in MDA-MB-231 breast cancer cells as expected, along with apoptotic morphology including cell shrinkage, membrane blebbing, and nuclear condensation (Fig. 1b). Interaction of hibiscus extract with conventional chemotherapies tamoxifen, taxol, and cisplatin in combination treatments